Arteleo Chemistry Journal

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Formation of Pyrazino[1,2,3-de]quinoxalines

5-Amino-3-phenyl-3,4-dihydro-2(1H)-quinoxalinone (194) gave 5-phenyl-2,3-dihydro-1H, 5H-pyrazino[1,2,3-de]quinoxaline-2,3,6(7H)-trione (195) [(COCl)2, Et3N: 30%];880 also analogs.880,1080

Formation of Pyrazino[2,3-g]quinazolines

Ethyl 7-amino-2,3-dimethyl-6-quinoxalinecarboxylate (196) and urea gave 7,8-dimethylpyrazino[2,3-g]quinazoline-2,4(1H, 3H)-dione (197) (neat reactants,